The orange way for
health and beauty.

The way to outer beauty leads more and more through inner support. A good example for a promising vegan supplement is the ingredient RED ORANGE COMPLEX™ (ROC). It is manufactured by the Italian company BIONAP and supplied by Vivatis Pharma.

Natural support to maintain healthy skin and decrease oxidative stress.

RED ORANGE COMPLEX™ is a standardized powder extract obtained from the juice of three pigmented varieties of the Sicilian blood orange (Moro, Tarocco and Sanguinello) grown exclusively in a particular area surrounding Europes most active volcano, Mt. Etna.

What it does

Thanks to the phenolic compounds (anthocyanins, flavanones, hydroxycinnamic acids) and ascorbic acid with antioxidant activity, ROC is able:
● To protect skin against UV-induced damage (cutaneous erythema) and control the hyperpigmentation (melanin production) and photoaging.
● To decrease oxidative stress and thus protect against its short and long-term health consequences in athletes engaged in regular training programs;

Skin protection is becoming increasingly important.

The increase in solar ultraviolet radiation (UVR) that reaches the Earth’s surface should make us reflect on the need to develop new approaches in protecting the skin from UVR exposure. RED ORANGE COMPLEX™ can be an answer to this.

Positive results of a brandnew study

A new randomized, double-blind, controlled study (June, 2022) was carried out in 110 subjects. The present study aims to evaluate the photoprotective and antiaging efficacy of RED ORANGE COMPLEX™ (100 mg/day). The intake of the product for 56 days was effective in improving the skin reaction to UV exposure; in increasing the skin antioxidant capacity as well as in decreasing UVA-induced lipid peroxidation; in increasing the skin moisturization, skin elasticity, and skin radiance; and in decreasing TEWL, the intensity of melanin staining inside dark spots, and wrinkle depth. The results suggest that the test product is effective in counteracting both the harmful effects of UVR exposure and aging signs.

The new results confirm previous studies and add to the positive effects for health and a more beautiful skin appearance.

Several clinical trials proved that RED ORANGE COMPLEX™ supplementation is able to decrease oxidative stress in subjects with compromised antioxidant defenses. In addition, ROC inhibits skin damage and contributes to the maintenance of healthy skin. It also reduces skin sensitivity to UV-induced erythema.

One example of a previous study, with a special focus on sportsmen.

The effect of ROC has been evaluated in a clinical study carried out:

  • on 18 sportsmens and 17 sedentary individuals
  • treated with 100 mg/day of ROC
  • for 2 months (2 capsules of 50 mg/day)

RED ORANGE COMPLEX™ was able to increase plasma concentration of biomarkers related to the presence of antioxidant endogenous substances (glutathione and its derivatives), such as thiolic groups-SH levels in sportsmen (a). Moreover, it can reduce oxidative stress biomarker values to physiological range, as shown in D-Roms test results (b).

Red Orange Extract™ is available in different formats

Tablet | Soft Capsule | Hard Capsule | Powder | Gummies | Beverages


  • Skin protection from UV damage (antiaging)
  • Scientifically-proven efficacy
  • Goes very well with collagen
  • 100% natural composition Good Agriculture Practices

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Do you need further information?

I would be happy to provide you with detailed studies and answer your question.

Moritz Dunkel
Head of Nutraceuticals

MD Quadratisch